April 1, 2013

Preventing Gestational Diabetes with a Supplement?

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pregnancyA small study published in Diabetes Care has given good reason to look twice at the supplementation of inositol during pregnancy to protect against gestational diabetes (GD).

The trajectory of GD ┬áhas risen, along with the statistics of T1D and T2D. Now that the diagnosis criteria for GD is becoming more stringent, it’s more likely that the diagnosis rate will rise.

In an attempt to help curtail the rate of GD diagnosis, a randomized controlled trial (RCT) measuring urinary inositol output was conducted. Inositol is found in many foods and enhances insulin action. Could supplementation with an inositol derivative protect against the development of GD?

Inositol is considered to be a B vitamin. There is no recommended daily intake (RDI) for inositol but the suggested intake is between 25 – 300 mg per day. The study tested between 200 mg per day to 4 grams per day.

The findings of the study show that subjects who developed GD had higher concentrations of inositol in their urine. The control group had comparatively less inositol in their urine and did not develop GD.

Hypothetically, researchers feel that it would be worthwhile to consider evaluating is dietary supplementation with inositol in high risk women, may be of value in protecting from the development of GD.

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