March 14, 2013

Salt in the Wounds of T1D Development

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salt-T1DSalt may be the most common seasoning in our diet. But could it cause the autoimmune attack leading to T1D?  

According to a study in Nature, salt might be responsible for an increase in the dispatch of cells that cause autoimmune diseases.

Researchers have long implicated lifestyle and diet as the reason for autoimmune disease in our society. There has been compelling trajectory data based on locations, populations, and disease occurrence throughout the world.

Researchers discovered that tissues store excess salt from the diet, and this salt triggers a series of reactions that causes an inflammatory response.This inflammatory response alarms the immune system to rescue the body from the attack.

The rescuing team is made up of T-cells. These T-cells are apparently aggravated to the extent that they no longer are able to discern self from non-self. In a fit of rage, they are no longer rescuing the body from attack, but launching one.

The idiom rubbing salt into a wound takes on new meaning in light of this study. T1D is a difficult situation. but adding excess salt to the equation may add fuel to the fire.

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