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beta cells (18)
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Shedding Skin to Make Insulin
Insulin is one of the gifts from the endocrine system, which means it comes from an organ that secretes directly into the bloodstream. The shocking turn of events was published in Cell Stem Cell with a study that explains how researchers have found a source of insulin-producing cells in the skin. The stonewall in finding […]
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One of Many Options to “Cure” T1D
A 12-year study of a type of antibody known as Ig-GAD2 has shown that it was able to prevent the immune system from attacking the insulin producing cells and causing T1D. Diabetes.co.uk reports on the promising decade long research. The fly in the ointment of Ig-GAD2 stopping the T1D attack was the speed at which the autoimmune attack took […]
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Hunting the Cause of LADA
What triggers adult autoimmune diabetes? It’s a fair question and a study answering this question was published in the Journal of Diabetes & Metabolism. The aim of this study was to identify a risk factor that precludes the diagnosis of adult-onset autoimmune diabetes and may prevalent the incidence of this type of diabetes. This form […]
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TUDCA is AWOL in T1D and T2D
Researchers have found that the cause of T1D may be something more than an autoimmune attack. Is there a weakness in the beta cells, themselves? The study was published in Science Translational Medicine. New research is hinting that a naturally occurring molecule called TUDCA could prevent T1D. The story goes back to the ER or […]
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Transplanting Islets into Bone Marrow
The location for islets have been toyed with for decades. Although they have been transplanted to the liver, some people cannot sustain this procedure based on their liver health. New research is finding that a potential landing zone for transplanted islets could be the bone marrow, as published in Diabetes. Historically, transplanted islets have been transfused through […]
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3D Method Used to Grow Micro Pancreas
Nowadays, every day tells news of a medical marvel. Today, the astonishing news is out of the journal Development showing how researchers have been able to grow a 3D micro pancreas. It sounds science fiction but it’s as non-fiction as science gets. The miniature pancreas was cultivated from progenitor cells. From this small step in creating […]
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People with T1D Producing Insulin
A study in Diabetologica describes how a certain percentage of people with T1D can be stimulated to produce insulin. This study may redefine the capabilities of people with the inability to produce insulin. Although people with T1D are thought to have no insulin production capability, this study has shown that some people in response to food, […]
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Insulin Making Cells Multiply in Test Tubes
There is a shortage of cold bodies to service the needs of people waiting for diabetes-curing islet cell transplants. The answer to this biological quagmire may be right around the corner. PLoS One has published a study showing that researchers have grown functioning insulin-producing cells in a test tube. “Until now, there didn’t seem to be […]
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Root Cause of T1D Discovered
Dr. Paolo Fiorina was looking for the molecular pathway that triggers diabetes, with the ultimate goal of finding a permanent cure. “In order to truly cure diabetes, we needed to pinpoint exactly why this happens. And then prevent it,” Fiorina says. Upon that premise, Dr. Fiorina and his team found the root cause of T1D: ATP/P2X7R, […]
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TEDDY Study
The objective of the TEDDY Study is to identify which molecular and environmental factors contribute to the development of T1D. The current findings are published in Diabetes Metabolism Research and Reviews. As with all biological circumstances, a person has a genetic blueprint in their DNA of what may or may not happen to them. Researchers […]
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