
The same gas that gives rotten eggs their offensive odor is produced by the human body. Hydrogen sulfide produced by the body has a number of biological signaling functions. Contrary to the way it smells in eggs, the purpose of hydrogen sulfide in humans is defensive.
Hydrogen sulfide (H2S) has been shown to have a potential protective role in a number of diseases including diabetes and various kidney disorders. Of course, as with many early discoveries in science, the mechanisms involved are still unclear.
Cells were cultured at a normal glucose concentration of approximately 5.5 mg/dL (a blood glucose of 100). The cells were then treated for 24 hours with different H2S concentrations.
There was a significant increase in HO-1 expression after treatment with the H2S. HO-1 appears in response to stress such as oxidative stress. Oxidative stress is what causes bad things to happen in the kidney.
These results suggest that H2S has a role in the regulation of HO-1 expression, and the ability to protect the kidney from oxidative stress damages. Now let’s find a way to encourage the body to produce a safe and nontoxic marinate of hydrogen sulfide.
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