
Secreted frizzled-related protein 4 (SFRP4) is a protein that in humans is encoded by the SFRP4 gene. SFRP4 influences islets and reduces glucose-induced insulin secretion. The overabundance of SFRP4 can be measured in people years before symptoms are detected for Type 2 diabetes.
People who have above-average levels of SFRP4 in the blood are five times more likely to develop diabetes in the next few years than those with below-average levels. Knowing ahead of time, before symptoms of diabetes begin to alarm patients of a potential diagnosis, people can proactively enact lifestyle changes to thwart a Type 2 diabetes diagnosis.
For as long as Type 2 diabetes has been researched, the Holy Grail of predicting islet inflammation has been a mystery. Now that researchers are able to connect the over expression of SFRP4 with islet inflammation years before a Type 2 diagnosis, the dots are forming a picture. Imagine a banner flying behind a plane reading: Fold! This is not your hand.
Very few people, if any, would volunteer to check their blood glucose levels several times a day. However, if you knew that blood glucose checks, medications, and the looming threat of diabetic complications could be in the cards – wouldn’t you want to know? A lifestyle change could deal you a new hand that helps you avoid the pitfalls of Type 2 diabetes.
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