May 27, 2013

New Treatment for Diabetes Wound Healing


woundsA  novel approach to treat diabetic foot ulcers, preventing amputations, may be in the near future for  people with diabetes and chronic wounds . An Umea University finding indicates a well-know plasma protein can be used to treat chronic diabetic wounds.

One of the greatest threats to people with diabetes is the loss of a limb due to amputation. These amputations are most often due to a foot ulcer and the preventative treatments to remove the affected limb.

The plasma protein  is plasminogen. The level of plasminogen does not increase and the inflammatory response is dulled. When plasminogen is injected around diabetic wounds, the healing process starts and the wound heals fully.

Furthermore, in chronic eardrum perforations, local injection and topical application of plasminogen also stimulates the healing and leads to complete healing.

Because the findings of these studies were so impressive, a controlled clinical study using human plasminogen to treat chronic wounds in humans is now planned. The ultimate goal is to develop plasminogen to a medicine for the treatment of various chronic wounds.

Amputation due to foot ulcers is a complication that affects someone with diabetes every 20 seconds. If this treatment correlates to a 100% wound healing rate, we may be looking at the final days of diabetic limb amputations.

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