February 14, 2013

Stomach bug may help control Diabetes


stomach_bugAt first glance, this headline comes across as a bit crass. If you cannot keep food down, eating is the last thing  on your min. However., there may be science behind this sizzle.

The study was published in PLoS ONE . Theoretically the study shows that the use of a stomach bacteria that is typically related to gastritis, ulcers, and gastric cancer may be helpful in a multitude of roles for controlling T2D.

Therapeutic use of this stomach bug may balance the stomach`s ecosystem, control  body weight and glucose tolerance.  The name of this stomach bug is Helicobacter pylori or H. pylori.

H. pylori is usually named in studies of gastric cancer and peptic ulcers. This time, it’s a possible route of treatment, rather than a cause of ailments.

The role of H. pylori is not just a hunch. It is known that H. pylori is the dominant member of the gastric microbiota and infects about half the people in the world. As the epidemic of T2D and obesity has increased, the population of H. pylori has decreased.

Researchers are asking if mouse models were to have the challenges of obesity and T2D – would H. pylori be of any help? Sure enough, a trial of gastric colonization with H. pylori exerts beneficial effects in mouse models of obesity and diabetes.

Is there any danger to a potentially harmful bacteria being used to treat obesity and T2D? Researchers believe that whether the infection is harmful or beneficial depends on the interaction between the genetic makeup of H. pylori and the host`s immune response.

Has the overconsumption of antibiotics evolved into an underwhelming number of gastric bacteria to keep us metabolically healthy? Only time will tell as these studies continue with H. pylori.

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