December 18, 2012

The Relationship between Eye and Kidney Blood flow in Type 2 Diabetes


bloodflowResearchers wanted to study the relationship between retinal blood flow and kidney function in patients with Type 2 diabetes.

The kidney blood flow is essential  to filter the blood. The retinal blood flow is essential to maintain vision. Lack of blood to either organ means lack of oxygen throughout the body. Most living things need oxygen to survive and this is true for organs, as well.

The study obtained the retinal blood flow (RBF) by simultaneously measuring the retinal vessel diameter and blood velocity. To determine if the RBF is affected in the presence of renal dysfunction, researchers also evaluated the renal function using the estimated glomerular filtration rate (GFR).

The study evaluated 169 eyes of 169 Japanese patients with Type 2 diabetes. The patients were divided into four groups based on the stage of chronic kidney disease (CKD): none, stage 1, stage 2, and stage 3.

The researchers found significant decreases in RBF with decreased vessel diameter but no difference in blood velocity in stage 3 CKD compared with the non-CKD group. Multiple regression analysis showed that the CKD stage was significantly and independently associated with decreased RBF.

The study results indicate that impaired kidney function might be associated with decreased blood flow to the eye. If it’s any consolation, perhaps Paxil can come to the rescue of the impaired vessels? Get on it GlaxoSmithKline. There may be a very pertinent use for this drug in a subclinical dose. Submit the NDA and begin the healing.

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